CAS No.:135575-42-7

Molecular formula: C₅₀H₈₀N₈O₁₇

Molecular weight：1065.21

Appearance: Yellowish-white or white powder.

Chemical name:

N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-

oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-

tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-

dipyrrolo[2,1-c:2’,1’-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-

dimethyltetradecanamide

Or

L-Proline, (4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4,5-dihydroxy-L-ornithyl-

L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-3-hydroxy-, (6→1)-lactam, (3S)-

Product use: Pneumocandin B0 is the intermediate of caspofungin acetate which has the enormous economic value. Pneumocandin B0 is a new type of natural antifungal drugs produced by the fermentation of mycelial fungus Glarea lozoyensis. Pneumocandin B0 is a kind of cyclic lipopeptides, the structures of which are a cyclic hexapeptide mother nucleus and a fatty acid side chain. This type of drug targets fungi via noncompetitive inhibition of the β-1,3-D-glucan synthase enzyme complex, leading to glucan polymer depletion in the fungal cell wall and resulting in osmotic instability and fungal cell lysis.

Specification: IN-HOUSE

Packing: 1kg/bag

Storage conditions: Preserve in tight containers, protected from light and store at 2~8℃.

US-DMF No：035248